Document Type : Review Paper
Fatemeh Zahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran
Midwifery and Reproductive Health Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran
School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
School of Pharmacy, Shaheed Beheshty University of Medical Sciences, Tehran, Iran.
Conventional treatment for primary dysmenorrhoea has a failure rate of 20% to 25% and may be contraindicated or not tolerated by some women. Herbal medicine may be a suitable alternative.
The objective of the manuscript, is determine the efficacy and safety of some Iranian herbal medicine for primary dysmenorrhea when compared with placebo, no treatment, and other treatment. For this target electronic searches of the Cochrane Menstrual Disorders and Dysmenorrhoea Group Register of controlled trials, Scopus, Google Scholar, Medline, Pubmed were performed to identify relevant randomized controlled trials (RCTs).
The study abstraction and quality assessment of all studies were undertaken following the detailed descriptions of these categories as described in the JADAD Criteria for Systematic Reviews of Interventions.
25 RCTs involving a total of women were included in the review. The review found promising evidence in the form of RCTs for the use of herbal medicine in the treatment of primary dysmenorrhoea compared with pharmacological treatment. However, the results were limited by methodological flaws. Further rigorous no penetrating placebo-controlled RCTs are warranted.
The review found promising evidence supporting the use of herbal medicine for primary dysmenorrhoea; however, results are limited by the poor methodological quality of the included trials.