Iranian Journal of Pharmaceutical Research

1. Nut Consumption and Lung Cancer Risk: Is Linoleic Acid the Secret Weapon?

Pages 1-2

Raffaella Mormile

2. Green Nanotechnology-based Gold Nanomaterials for Hepatic Cancer Therapeutics: A Systematic Review

Pages 3-17

Hamed Barabadi; Thomas J. Webster; Hossein Vahidi; Hamed Sabori; Kaveh Damavandi Kamali; Fereshteh Jazayeri Shoushtari; Mohammad Ali Mahjoub; Masoumeh Rashedi; Ebrahim Mostafavi; David Medina Cruz; Omid Hosseini; Muthupandian Saravanan

3. The Effectiveness of Intranasal Oxytocin on Addiction Severity Index and Anhedonia Symptoms in an Alcoholic Case with Oropharyngeal Cancer, a Protocol for a Single-case Experimental Design Pilot Study

Pages 18-23

Bijan Pirnia; Mostafa Hamdieh; Maryam Kazemi Ashtiani; Parastoo Malekanmehr; Kambiz Pirnia; Alireza Zahiroddin; Paria Sadeghi

4. A Randomized, Open, Single-Centre, Crossed Study of the Effect of Food on the Pharmacokinetics of One Oral Dose of Alﬂutinib Mesylate Tablets (AST2818) in Healthy Male Subjects

Pages 24-33

Songlin Zhu; Jun Deng; Qi Tang; Jianfu Heng; Jingjing Qu; Yong Chen; Xue Chen; Nong Yang; Xiaobao Liu; Kunyan Li

5. In-vivo Anti-inflammatory Activity of Hydrocotyle umbellata L. aerial parts and Isolation of the Main Phytochemicals

Pages 34-44

Sherif A. Hamdy; Esther T. Menze; Hala M. El Hefnawy; Shadia M. Azzam; Elsayed A. Aboutabl

6. Preparation, Statistical Optimization and In-vitro Characterization of a Dry Powder Inhaler (DPI) Containing Solid Lipid Nanoparticles Encapsulating Amphotericin B: Ion Paired Complexes with Distearoyl Phosphatidylglycerol

Pages 45-62

Ehsan Mehrabani Yeganeh; Hossein Bagheri; Reza Mahjoub

7. Fabrication and In-vitro Evaluation of Buccal Mucoadhesive Tablet of Meloxicam

Pages 63-76

Mahshid Arabi; Seyed Alireza Mortazavi; Zahra Jafari Azar; Hassan Farhadnejad; Golnoosh Alipour Haris; Yousef Fatahi

8. The Contribution of VKORC1 and CYP2C9 Genetic Polymorphisms and Patients’ Demographic Characteristics with Warfarin Maintenance Doses: A Suggested Warfarin Dosing Algorithm

Pages 77-85

Esmat Khaleqsefat; Mohammad Khalaj-Kondori; Mortaza Jabarpour Bonyadi; Hamid Soraya; Behnam Askari

9. The Effect of Treating Vitamin D Deficiency or Insufficiency on Serum Adiponectin, Leptin and Insulin Resistance of Type 2 Diabetes Mellitus Patients: A Pilot Study

Pages 86-94

Afshin Gharekhani; Farzad Najafipour; Hananeh Baradaran; Parisa Tagarrobi; Haleh Rezaee

10. Donepezil and Rivastigmine: Pharmacokinetic Profile and Brain-targeting After Intramuscular Administration in Rats

Pages 95-102

Jana Zdarova Karasova; Martina Hrabinova; Marketa Krejciova; Daniel Jun; Kamil Kuca

11. Spectrophotometric Methods for Determination of Sunitinib in Pharmaceutical Dosage Forms Based on Ion-pair Complex Formation

Pages 103-109

Effat Souri; Eynollah Amoon; Nazanin Shabani Ravari; Fereshteh Keyghobadi; Maliheh Barazandeh Tehrani

12. Neuro-behavioral Profile and Toxicity of the Essential Oil of Dorema ‎ammoniacum Gum as an Anti-seizure, Anti-Nociceptive, And Hypnotic Agent with Memory-‎enhancing Properties in D-Galactose Induced Aging Mice

Pages 110-121

Reza Jahani; Mona Khoramjouy; Azadeh Nasiri; Maryam Sojoodi Moghaddam; Yousef Asgharzadeh Salteh; Mehrdad Faizi

13. Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway

Pages 122-133

Shokoofe Noori; Mostafa Rezaei Tavirani; Niloofar Deravi; Mohammad Ismaiil Mahboobi Rabbani; Afshin Zarghi

14. Synthesis, Molecular Docking and Cytotoxic Activity Evaluation of Organometallic Thiolated Gold(I) Complexes

Pages 134-143

Zeinab Faghih; Alireza Yazdani Kachoei; Hossein Alizadeh; Suphia Emamdoost; Shima Shirkhan; Masood Fereidoonnezhad

15. Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519

Pages 144-155

Atieh Pourbagheri-Sigaroodi; Ava Safaroghli-Azar; Mehrnoosh Shanaki; Amir-Mohammad Yousefi; Ali Anjam-Najmedini; Davood Bashash

16. Synthesis and Bioactivity of a Cyclopolypeptide from Caribbean Marine Sponge

Pages 156-170

Rajiv Dahiya; Stacy Rampersad; Terry G. Ramnanansingh; Komalpreet Kaur; Ramninder Kaur; Rita Mourya; Suresh V. Chennupati; Richard Fairman; Nigel K. Jalsa; Ajay Sharma; Shivkanya Fuloria; Neeraj Fuloria

17. Metal (II) Complexes of Fluconazole: Thermal, XRD and Cytotoxicity Studies

Pages 171-182

Syed Imran Ali; Zi-Ning Lei; Mohsin Ali; Konatsu Kojima; Mansoor Ahmed; Richard Peng; Dong-Hua Yang; Syed Moazzam Haider; Seyed Abdulmajid Ayatollahi; Zhe-Sheng Chen

18. Development of a GC-MS Method for Determination of various Polycyclic Aromatic Hydrocarbons in Iranian Traditional and Semi-industrial Taftoon Bread

Pages 183-194

Vahideh Moradi; Seyed Mahdi Seyedain Ardabili; Attaollah Shakoori; Seyed Ebrahim Hoseyni

19. Synthetic Biology Based on Genetic Logic Circuit, Using the Expression of Drug Resistance, BCRP Pump in MCF-7 Cancer Cell Line

Pages 195-205

Marzieh Gerami; Modjtaba Emadi-Baygi; Mohammad Eshghi; Fatemeh Elahian; Razieh Heidari; Mehdi Hosseinzadeh

20. Expression, Purification and Docking Studies on IMe-AGAP, the First Antitumor-analgesic Like Peptide from Iranian Scorpion Mesobuthus eupeus

Pages 206-216

Zeinab Dehghan; Hoda Ayat; Ali Mohammad Ahadi

21. Antitumor Activity and Mechanism Study of Riluzole and Its Derivatives

Pages 217-230

Xiang-Long Wu; Liu Liu; Qing-Chuan Wang; Hai-Fang Wang; Xiang-Rong Zhao; Xu-Bin Lin; Wen-Jun Lv; Yin-Bo Niu; Ting-Li Lu; Qi-Bing Mei

22. Ficus carica L. latex: Possible chemo-preventive, apoptotic activity and safety assessment

Pages 231-240

Fereshteh Jeivad; Nargues yassa; Seyed Nasser Ostad; zahra hasannejad; Gholamreza Hassanzadeh Gheshlagh; Omid Sabzevari

23. Effects of fish oil supplementation on pregnancy outcomes in pregnant women referred to Kosar Hospital

Pages 241-247

Nazanin Gholami; Shokohossadat Abotorabi; Fatemeh Lalooha; Sonia Oveisi

24. Trimetazidine increases plasma MicroRNA-24 and MicroRNA-126 levels and improves dyslipidemia, inflammation and hypotension in diabetic rats

Pages 248-257

Fatemeh Ramezani- Ali akbari; Mohammad Badavi; Mahin Dianat; Seyyed Ali Mard; Akram Ahangarpour

25. Approaches for the Treatment of SARS-CoV-2 Infection: A Pharmacologic View and Literature Review

Pages 258-281

Hajar Mohammadi Barzelighi; Bahram Daraei; Farzaneh Dastan

26. Frequency of antimicrobial resistance and class 1 and 2 integrons in Escherichia coli strains isolated from urinary tract infections

Pages 282-287

Mahboobe Mirnezami; Reza Ranjbar; Mohammad Niakan; Mohammad Hossein Ahmadi

27. Isolation of polyclonal scFv fragments against venomous snakes of Iran and evaluation of its capability in neutralizing the venom

Pages 288-296

Maryam Kadkhodazadeh; Masoumeh Rajabibazl; Mohammad Hassan Motedayen; Solmaz Shahidi; Ziba Vaise Malekshahi; Azam Rahimpour; Maral Yarahmadi

28. Optimization of buffer additives for efficient recovery of hGM-CSF from inclusion bodies using response surface methodology

Pages 297-309

Mina Ahmadian; Ali Jahanian-Najafabadi; Vajihe Akbari

29. Protective effects of a nano-formulation of curcumin against cuprizone-induced demyelination in the mouse corpus callosum

Pages 310-320

Mahsa Motavaf; Majid Sadeghizadeh; Sadegh Babashah; Leila Zare; Mohammad Javan

30. Multi-drug resistance of Staphylococcus aureus strains in Baqiyatallah hospital: a primary step towards digital health biomonitoring systems

Pages 321-328

Ahmad Reza Katouzian; Abbas Ali Imani Fooladi; Ramezan Ali Taheri; Saba Vatanpour

31. Structure prediction and expression of modified rCTLA4-Ig as a blocker for B7 molecules

Pages 329-348

Hossein Mahdizadeh; Jafar Salimian; Zahra Noormohammadi; Jafar Amani; Raheleh Halabian; Yunes Panahi

32. Hypericin induces apoptosis in AGS cell line with no significant effect on normal cells

Pages 349-357

Misagh Naderi; Mahtab Rahmani Cherati; Ali Mohammadian; Mohammad Baghery Bidhendy; Saeedeh Ghiasvand; Hadi Zare Marzouni; Hoda Aryan; Ehsan Jangholi; Mohammad Amin Javidi

33. Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against Ehrlich ascites carcinoma-bearing BALB/c mice

Pages 358-369

Erhan Bozkurt; Emre Atay; Gökhan Pektaş; Ayşe Ertekin; Ayhan Vurmaz; Omer Adil Korkmaz; Gokhan Sadi; Esra Aslan; Oğuz Han Koca; Mehmet Bilgehan Pektaş

34. Synthesis of Novel Peptides Using Unusual Amino Acids

Pages 370-382

Bahareh Talaei; Vaezeh Fathi Vavsari; Saeed Balalaie; Armin Arabanian; Hamid Reza Bijanzadeh

35. Evaluation of swab and rinse sampling procedures and recovery rate determination in cleaning validation considering various surfaces, amount and nature of the residues and contaminants

Pages 383-390

Somayeh Lamei Ramandi; Ramin Asgharian

36. Flavonoid calycopterin induces apoptosis in human prostate cancer cells in vitro

Pages 391-401

Reza Lotfizadeh; Houri Sepehri; Farnoosh Attari; Ladan Delphi

37. Significant anticancer activity of a venom fraction derived from the Persian Gulf sea anemone, Stichodactyla haddoni

Pages 402-420

Ziba Moghadasi; Delavar Shahbazzadeh; Shahla Jamili; Nariman Mosaffa; Kamran Pooshang Bagheri

38. Bio-removal of Heavy Metals using Iron-oxidizing Bacteria: A Novel Approach in Environmental Biotechnology

Pages 421-429

Sareh Farahani; Abbas Akhavan Sepahi; Seyed Abbas Shojaosadati; Farzaneh Hosseini

39. The effect of Erythropoietin administration on the serum level of YKL-40, pro-BNP and IL-6 in coronary surgery patients

Pages 430-439

Mahnoosh Foroughi; Zohre Mohammadi; Masoud Majidi Tehrani; Mahmood Bakhtiyari; Ali Dabbagh; Mostafa Haji mollahoseini

40. Protective effects of crocin against hepatic damages in D-galactose aging model in rats

Pages 440-450

Seyedeh Farzaneh Omidkhoda; Soghra Mehri; Somaye Heidari; Hossein Hosseinzadeh

41. Comparison of Mirtazapine and Olanzapine on Nausea and Vomiting Following Anthracycline-Cyclophosphamide Chemotherapy Regimen in Patients with Breast Cancer

Pages 451-464

Alimohammad Maleki; Mojtaba Ghadiyani; Jamshid Salamzadeh; Sina Salari; Seyedshahab Banihashem; Maria Tavakoli-Ardakani

42. Development and Characterization of Niosomal Gel System using Lallementia royaleana Benth. Mucilage for the Treatment of Rheumatoid Arthritis

Pages 465-482

Snigdha Bhardwaj; Sonam Bhatia

43. A novel 1,3-β-glucanase gene from the metagenomic expression library of Achatina fulica’s digestive gland

Pages 483-493

Maris Kurniawati; Purkan Purkan; Sri Sumarsih; Afaf Baktir

44. Pharmacological evidence for curcumin neuroprotective effects against lead-stimulated neurodegeneration: possible role of Akt/GSK3 signaling pathway

Pages 494-508

Negin Goudarzi; Sanaz Mohammad Valipour; Akram Nooritahneh; Majid Motaghinejad; Manijeh Motevalian; Sepideh Safari; Mina Gholami; Safieh Vatandour; Malek Hekmati