Iranian Journal of Pharmaceutical Research

1. Thalidomide against Coronavirus Disease 2019 (COVID-19): A Medicine with a Thousand Faces

Pages 1-2

Farzaneh Dastan; Payam Tabarsi; Majid Marjani; Afshin Moniri; Seyed MohammadReza Hashemian; Maria Tavakoli-Ardakani; Ali Saffaei

2. CB2 Agonist (AM1241) Improving Effect on Ovalbumin-Induced Asthma in Rats

Pages 3-17

Ali PARLAR; Seyfullah ARSLAN

3. Determination of mirtazapine and desmethyl mirtazapine in human plasma by a new validated HPLC ultraviolet method with a simple and reliable extraction method: Application to therapeutic drug monitoring study by 62 real patient plasma

Pages 18-30

Emrah Dural; Nilay Sedes Başkak; Hatice Özcan; Yağmur Kır Baskak; Bora Başkak; Halit Sinan Süzen

4. A Fourteen-day Experience with Coronavirus Disease 2019 (COVID-19) Induced Acute Respiratory Distress Syndrome (ARDS): An Iranian Treatment Protocol

Pages 31-36

Hamidreza Jamaati; Farzaneh Dastan; Payam Tabarsi; Majid Marjani; Ali Saffaei; Seyed MohammadReza Hashemian

5. Silencing of nucleostemin by siRNA induces apoptosis in MCF-7 and MDA-MB-468 cell lines

Pages 37-45

Mahdiyeh Moudi; Ramin Saravani; Saman Sargazi

6. Raise up of Scopolamine In Hairy Roots Via Agrobacterium rhizogenes ATC15834 as Compared With Untransformed Roots In Atropa komarovii

Pages 46-56

ofelia banihashemi; Ramazan Ali Khavarinejad; Narguess yassa; Farzaneh Najafi

7. Early Graft Function in Deceased Donor Renal Recipients: Role of N-Acetylcysteine

Pages 57-67

Atieh Modarresi; Mohsen Nafar; Zahra Sahraei; Jamshid Salamzadeh; Shadi Ziaie

8. Utilization Evaluation of Human Papilloma Virus Vaccine (GARDASIL®) In Iran; A Cross-Sectional Study.

Pages 68-76

Fatemeh Mohammad pour; Ava Mnsouri; Molouk Hadjibabaie

9. Phytochemical study of Tanacetum sonbolii aerial parts and the antiprotozoal activity of its components

Pages 77-83

Sahar Mofidi Tabatabaei; Mahdi Moridi Farimani; Samad Nejad-Ebrahimi; Peyman Salehi

10. 3-Hydroxypyrimidine-2,4-dione derivatives as HIV Reverse Transcriptase-Associated RNase H Inhibitors: QSAR analysis and molecular docking studies

Pages 84-97

Azar Mostoufi; Nargese Chamkouri; Samaneh Kordrostami; Elham Alghasibabaahmadi; Ayyub Mojaddami

11. Phytochemical study of oleuropein and its therapeutic effects in improving seizure, oxidative stress and cognitive disorder in pentylenetetrazole kindling mouse model of epilepsy

Pages 98-110

Samira Asgharzadeh; zahra Rabiei; sana Rabiei; Elham Bijad; Mahmoud Rafieian- Kopaei

12. Evaluation of neuroprtective effects of L-Carnitine and Fat emulsion in the CVA patients: a prospective, randomized, double blind, clinical trial

Pages 111-119

kaveh kazemian; Shahram Ala; Mojtaba Mojtahedzadeh; Mahmoud Abedini; Abbas Alipour; Saeid Abediankenari; Mohammadreza Rafati; Ali Abaskhanidavanloo; Fatemeh Mohajerani

13. Synthesis of Flower-like Nickel Hydroxide Nanosheets and Application in Electrochemical Determination of Famotidine

Pages 120-137

Rezvan Dehdari Vais; Hossein Yadegari; Hossein Heli

14. Design and Evaluation of Losartan Transdermal Patch by Using Solid Microneedles as A Physical Permeation Enhancer

Pages 138-152

Ericka Anguiano Almazan; Pablo Serrano Castañeda; Roberto Diaz Torres; Jose Escobar-Chavez

15. NF-κB-dependent Mechanism of Action of c-Myc Inhibitor 10058-F4: Highlighting a Promising Effect of c-Myc Inhibition in Leukemia Cells, Irrespective of p53 Status

Pages 153-165

Mohammad Sayyadi; Ava Safaroghli-Azar; Majid Safa; Hassan Abolghasemi; Majid Momeny; Davood Bashash

16. Comprehensive Evaluation of Gene Expression in Negative and Positive Trigger-based Targeting Niosomes in HEK-293 Cell Line

Pages 166-180

Mahmood Barani; Masoud Torkzadeh-Mahani; Mohammad Mirzaei; Mohammad Hadi Nematollahi

17. Design and Synthesis of Novel 1-Hydroxy-2,4,5-triaryl Imidazole Derivatives as Anti-Cytokine Agent

Pages 181-191

Zahra Haghighijoo; Omidreza Firuzi; Savis Meili; Najmeh Edraki; Mehdi Khoshneviszadeh; Ramin Miri

18. In-vitro Study of Hottentotta Schach Crude Venom Anticancer Effects on MCF-7 and Vero Cell Lines

Pages 192-202

Saeed Dezianian; Jamil Zargan; Hamid Reza Goudarzi; Ashkan Haji Noormohamadi; Mohsen Mousavi; Hani Keshavarz Alikhani; Behrooz Johari

19. Attributes Development for Pharmaceutical Subsidization: A Qualitative Study

Pages 203-217

Gita Afsharmanesh; Gholamhossein Mehralian; Farzad Peiravian

20. Analgesic, Anti-inflammatory and In-vitro Hyaluronidase Inhibitory Properties of the Leaf Extract and solvent fractions of Otostegia fruticosa (Forssk.) Schweinf. ex Penzig.

Pages 218-230

Tiegsti Bahta; Aman Karim; Gomathi Periasamy; Gereziher Gebremedhin; Najeeb- ur-Rehman; Helen Bitew; Kalay Hagazi

21. Antidiabetic Properties of Hydroalcoholic Leaf and Stem Extract of Levisticum officinale: An implication for α-amylase Inhibitory Activity of Extract Ingredients through Molecular Docking

Pages 231-250

Nahid Ghaedi; Iran Pouraboli; Nayereh Askari

22. Docking, Synthesis and Evaluation of the Antifungal Activity of Pyrimido[4,5-b]Quinolins

Pages 251-259

Reza Araqi; Bi Bi Fatemeh Mirjalili; Leila zamani; Soghra Khabnadideh; Kamiar Zomorodian; Zeinab Faghih; Hamhdreza Arabi

23. LED photo-polymerization, a novel strategy for triggered release liposomes

Pages 260-270

Afsoon Akbarzadeh; Pezhman Sasanpour; Hamid Reza Moghimi

24. Therapeutic Potential of Nanoparticle-loaded Hydroxyurea on Proliferation of Human Breast Adenocarcinoma Cell Line

Pages 271-281

Fateme Azemati; Bahman Jalali Kondori; Hadi Esmaeili Gouvarchin Ghaleh

25. Chemical Composition, Antioxidant, Genotoxique and Antigenotoxic Potentials of Phlomis Bovei De Noé Aerial Parts

Pages 282-291

Nabila Zaabat; Anne-Emmanuelle Hay; Serge Michalet; Inès Skandrani; Leila Chekir-Ghedirac; Marie-Geneviève Dijoux-Francaa; Salah Akkal

26. Improvement of Ocular Efficacy of Levofloxacin by Bioadhesive Chitosan Coated PLGA Nanoparticles: Box-Behnken Design, In-vitro Characterization, Antibacterial Evaluation and Scintigraphy Study

Pages 292-311

Ameeduzzafar Zafar; Nazia Khan; Nabil K Alruwaili; Syed Nasir Abbas Bukhari; Bader Alsuwayt; Muhammad Afzal; Sana Akhtar; Mohd Yasir; Mohammed Elmowafy; khaled Shalaby; Asgar Ali

27. Therapeutic Effect of Carvacrol-loaded Albumin Nanoparticles on Arthritic Rats

Pages 312-320

Nasser Gholijani; Samira-Sadat Abolmaali; Kurosh Kalantar; Mohammad-Hadi Ravanrooy

28. Acetone Fraction of the Red Marine Alga Laurencia Papillosa Reduces the Expression of Bcl-2 Anti-apoptotic Marker and Flotillin-2 Lipid Raft Marker in MCF-7 Breast Cancer Cells

Pages 321-330

Josiane Elia; Karina Petit; Jean-Michel Huvelin; Mona Tannoury; Mona Diab-Assaf; Delphine Carbonnelle; Hassan Nazih

29. Noscapine Modulates Neuronal Response to Oxygen-glucose Deprivation/Reperfusion Injury Via Activation of Sigma-1 Receptor in Primary Cortical Cultures

Pages 331-342

Gelareh Vahabzadeh; Nahid Rahbar-Roshandel; Soltan-Ahmad Ebrahimi

30. Exogenous Ghrelin Could Not Ameliorate 3,4-methylenedioxymethamphetamine-induced Acute Liver Injury in The Rat: Involved Mechanisms

Pages 343-354

Ravieh Golchoobian; Fatemeh Nabavizadeh; Mehrdad Roghani; Alireza Foroumadi; Maryam Izad; Maryam Bahrami; Hafseh Fanaei

31. A Preliminary Study of NER and MMR Pathways Involved in Chemotherapy Response in Bladder Transitional Cell Carcinoma: Impact on progression-free survival

Pages 355-365

Vahideh Montazeri; Mohammad Hossein Ghahremani; Hamed Montazeri; Mandana Hasanzad; Majid Safavi; Mohsan Ayati; Mohammad Chehrazi; Baharak Arefi Moghaddam; Seyed Nasser Ostad

32. Preparation, optimization and characterization of chitosan-coated for solubility enhancement of Furosemide: A model BCS IV drug

Pages 366-382

Mohammad Moslehi; Seyed Alireza Mortazavi; Amir Azadi; Samaneh Fateh; Mehrdad Hamidi; Mohsen Foroutan

33. Noncompetitive inhibition of bovine liver catalase by lawsone: Kinetics, binding mechanism and in silico modeling approaches

Pages 383-397

Simin Khataee; Gholamreza Dehghan; Samaneh Rashtbari; Siavoush Dastmalchi; Mehrdad Iranshahi

34. STAT3-mediated apoptotic-enhancing function of sclareol against breast cancer cells and cell sensitization to cyclophosphamide

Pages 398-412

Havva Afshari; Mitra Nourbakhsh; Niloufar Salehi; Mohammad Mahboubi_Rabbani; Afshin Zarghi; Shokoofe Noori

35. Development of a sensitive and rapid method for determination of acrylamide in bread by LC-MS/MS and analysis of real samples in Iran

Pages 413-423

Samira Eslamizad; Farzad Kobarfard; Kimia Tabib; Hassan Yazdanpanah; Jamshid Salamzadeh

36. Antioxidant Activity and Hemocompatibility Study of Quercetin Loaded Plga Nanoparticles

Pages 424-435

Serap Derman; Deniz Uzunoglu; Tayfun Acar; Tulin Ozbek Arasoglu; Samet Ucak; Veli Ozalp; Banu Mansuroglu

37. Isolation, purification and antioxidant activity of the polysaccharides from Chinese truffle Tuber sinense

Pages 436-447

Caihong Zeng; Xiaoyan Chen; Wenwen Jiang; Yanling Liu; Chunjuan Fang

38. Erythromycin releasing PVA/sucrose and PVA/honey hydrogels as wound dressings with antibacterial activity and enhanced bio-adhesion

Pages 448-464

Shahrzad Fathollahipour; Mojtaba Koosha; Javad Tavakoli; Susan Maziarfar; jalil fallah mehrabadi

39. Logic of Selecting Suitable Dissolution Parameters in New Drug Formulations Based on A BCS Approach

Pages 465-486

Raúl Medina-López; Edgar E. Arregui; Edson J. Aranda; Luis A. Moreno-Rochaa; Marcela Hurtado; Helgi Jung-Cook; Sally A. Helmy

40. Novel Bi-heterocycles as Potent Inhibitors of Urease and Less Cytotoxic Agents: 3-({5-((2-Amino-1,3-thiazol-4-yl)methyl)-1,3,4-oxadiazol- 2-yl}sulfanyl)-N-(un/substituted-phenyl)propanamides

Pages 487-506

Muhammad Athar Abbasi; Muhammad Shahid Ramzan; Aziz-ur- Rehman; Sabahat Zahra Siddiqui; Mubashir Hassan; Syed Adnan Ali Shah; Muhammad Ashraf; Muhammad Shahid; Sung-Yum Seo