Iranian Journal of Pharmaceutical Research

1. Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents

Pages 1-12

Ali Imani; Sepehr Soleymani; Rouhollah Vahabpour; Zahra Hajimahdi; Afshin Zarghi

2. Rapid Detection of Adulteration in Dendrobium Huoshanense with Dendrobium Henanense by ATR-FTIR Combined with Multivariate Methods

Pages 13-19

Jing-Wen Hao; Xiao-Quan Liu; Nai-Dong Chen; An-ling Zhu

3. Trust-building in the Pharmacist-patient Relationship: A Qualitative Study

Pages 20-30

Rasool Esmalipour; Pooneh Salari; Amirahmad Shojaei

4. Occurrence of Aflatoxins in Commercial Cereal-based Baby Foods in Iran: A Probabilistic Risk Assessment to Health

Pages 31-45

Moein Bashiry; Hassan Yazdanpanah; Ehsan Sadeghi; Sajad Shokri; Leila Mirmoghtadaie; Amir Mohammad Mortazavian; Abdorreza Mohammadi; Amene Nematollahi; Ehsan Hejazi; Hedayat Hosseini

5. Preliminary Study on Hepatoprotective Effect and Mechanism of (-)-Epigallocatechin-3-gallate against Acetaminophen-induced Liver Injury in Rats

Pages 46-56

Yongxu Lin; Juan Huang; Tingfang Gao; Yuanzi Wu; Da Huang; Fen Yan; Zuquan Weng

6. Comparison of HPLC and UV Spectrophotometric Methods for Quantification of Favipiravir in Pharmaceutical Formulations

Pages 57-65

İbrahim A Bulduk

7. Psychiatric Adverse Drug Reactions and Potential Anti-COVID-19 Drug Interactions with Psychotropic Medications

Pages 66-77

Parisa Ghasemiyeh; Negar Mortazavi; Iman Karimzadeh; Afsaneh Vazin; Laleh Mahmoudi; Ebrahim Moghimi Sarani; Ashkan MohammadSadeghi; Mina Shahisavandi; Ali Kheradmand; Soliman Mohammadi-Samani

8. Exploration of Inbuilt Novel Properties as Bioretardant Cum Stabilizer of Isolated Biopolymer from Fragaria ananassa in Delivery of Nanosized Phenytoin

Pages 78-93

Sushant Kumar; N.V. Satheesh Madhav

9. The Impact of Inflation and Its Uncertainty on Pharmaceutical Prices: Evidence from Iran

Pages 94-101

Maryam Soleimani Movahed; Aziz Rezapour; Sajad Vahedi; Hassan Abolghasem Gorji; Rafat Bagherzadeh; Ali Nemati; Gholamreza Nemati; Saeed Mohammad-pour

10. Benefits and Risks of Melatonin in Hepatic and Pancreatic Disorders; A Review of Clinical Evidences

Pages 102-109

Saeed Abdi; Mohammad Abbasinazari; Sara Ataei; Neda Khanzadeh-Mogaddam; Negin Keshvari

11. Chemical Variation, Antimicrobial, Nitric Oxide Scavenging Activities and Tyrosinase Inhibition of Essential Oils and Solvent Extracts from Filipendula vulgaris Moench Growing in Turkey

Pages 110-120

Seda - Fandakli; Büşra Korkmaz; Özlem Faiz; Gözde Kiliç; İshak Erik; Salih Terzioğlu; Nurettin Yayli

12. The Design, Synthesis and Evaluation of Rho-kinase Inhibitory Activity of 4-aryl-thiazole-2-amines

Pages 121-131

Linan Wang; Ben Ouyang; Meixia Fan; Junhui Qi; Lei Yao

13. An Observational Study on the Application of the Second-generation Radiopaque Subcutaneous Implant

Pages 132-139

Xu Xiaoou; Zhang Xiao Juan; Yang Xueniu

14. Biological Activities and the Essential Oil Analysis of Cousinia harazensis and C. calocephala

Pages 140-150

Ebrahim Salimi-Sabour; Farshad H. Shirazi; Arash Mahboubi; Faraz Mojab; Mahboubeh Irani

15. Ultrasound and Sonogenetics: A New Perspective for Controlling Cells with Sound

Pages 151-160

Seyedeh Sara Azadeh; Parinaz Lordifard; Mohammad Hasan Soheilifar; Gholamreza Esmaeeli Djavid; Hoda Keshmiri Neghab

16. Novel Cytotoxic Phenanthro-triazine-3-thiol Derivatives as Potential DNA Intercalators and Bcl-2 Inhibitors

Pages 161-177

Mehdi Khoshneviszadeh; Omidreza Firuzi; Malihe Aminsafaee; Masoud Kashefizadeh; Sara Ranjbar; Zahra Rezaei; Hossein Sadeghpur; Farshid Zargari; Ramin Miri; Najmeh Edraki

17. Efficacy and Safety of 0.25% Timolol Gel in Healing Split-Thickness Skin Graft Site

Pages 178-186

Amirhossein Ghanbarzamani; Ebrahim Salehifar; Abdolreza Jafarirad; Mohammad Hossein Hesamirostami; Ali Bagherzadehsaba; Majid Saeedi; Monireh Ghazaeian; Ghasemali Khorasani; Mahmoud Moosazadeh

18. An Overview on Quantum Dot-based Nanocomposites for Electrochemical Sensing on Pharmaceutical Assay

Pages 187-203

Leyla Karadurmus; Goksu Ozcelikay; Sena Vural; Sibel A. Ozkan

19. Inhibition of Different Pain Pathways Attenuates Oxidative Stress in Glial Cells: A Mechanistic View on Neuroprotective Effects of Different Types of Analgesics

Pages 204-215

Mohammad Reza Eskandari; Parivash Eftekhari; Samin Abbaszadeh; Maryam Noubarani; Bijan Shafaghi; Jalal Pourahmad

20. Adjunct Hypertonic Saline in Patients with Diffuse Edema Due to Heart Failure: A Randomized Double-Blinded Clinical Trial

Pages 216-222

Mohammad Parsa Mahjoob; Farnaz Barzi; Amirahmad Nassiri; Alireza Kaveh; Mahshid Haghi; Mahshad Ghoddusi; Mohammad Sistanizad

21. Private Demand for Covid-19 Vaccine: A Contingent Assessment from a Low-and Middle-income Country

Pages 223-234

Zahra Meshkani; Leila Zarei; Narges Hajimoladarvish; Jalal Arabloo; Aziz Rezapour; Hiro Farabi; Najmeh Moradi

22. Assessment of Cytotoxic and Apoptotic Effects of Salvia syriaca L. in Colorectal Adenocarcinoma Cell Line (Caco-2)

Pages 235-242

Şevki Arslan; Kübra Kocabiyik; Doğukan Mutlu; Gürkan Semiz

23. Validation of a Multiclass Method for the Screening of 15 Antibiotic Residues in Milk Using Biochip Multi-array Technology and Its application to Monitor Real Samples

Pages 243-253

Hassan Yazdanpanah; Arash Mahboubi; Samira Eslamizad; Zakieh Karimi; Elham Rashidi; Jamshid Salamzadeh

24. Application of QSAR Method in the Design of Enhanced Antimalarial Derivatives of Azetidine-2-carbonitriles, their Molecular Docking, Drug-likeness, and SwissADME Properties

Pages 254-270

Zakari Ya'u Ibrahim; Adamu Uzairu; Gideon Adamu Shallangwa; Stephen Eyije Abechi

25. Development of Novel Adhesive Bilayer Lyophilized Wafer of Moxifloxacin as a Modern Wound Dressing

Pages 271-284

Hossein Jafari; Vahid Ramezani; Mohsen Nabi-Meibodi; Ali Mohammad Ranjbar

26. Different Respiratory Samples for COVID-19 Detection by Standard and Direct Quantitative RT-PCR: A Literature Review

Pages 285-299

Maryam Ahmadzadeh; Hossein Vahidi; Arash Mahboubi; Fariba Hajifathaliha; Leila Nematollahi; Elham Mohit

27. PMSF Attenuates Morphine Antinociceptive Tolerance and Dependence in Mice: Its Association with the Oxidative Stress Suppression

Pages 300-309

Ehsan Asadi Akbarabadi; Hossein Rajabi Vardanjani; Shahrzad Molavinia; Marzieh Pashmforosh; Mohammad Javad Khodayar

28. Effect of Zebularine in Comparison to Trichostatin A on the Intrinsic and Extrinsic Apoptotic Pathway, Cell Viability, and Apoptosis in Hepatocellular Carcinoma SK-Hep 1, Human Colorectal Cancer SW620, and Human Pancreatic Cancer PaCa-44 Cell Lines

Pages 310-323

Masumeh Sanaei; Fraidoon Kavoosi

29. Histone Deacetylase Inhibitors, Intrinsic and Extrinsic Apoptotic Pathways, and Epigenetic Alterations of Histone Deacetylases (HDACs) in Hepatocellular Carcinoma

Pages 324-336

Masumeh Sanaei; Fraidoon Kavoosi

30. The Feasibility Study of Plasma-activated Water as Physical Therapy to Induce Apoptosis in Melanoma Cancer Cells In-vitro

Pages 337-350

Hamed Mahdikia; Babak Shokri; Keivan Majidzadeh-A

31. Promising Hybrids Derived from S-Allylcysteine and NSAIDs Fragments against Colorectal Cancer: Synthesis, In-vitro Evaluation, Drug-Likeness and In-silico ADME/tox Studies

Pages 351-367

Angie Herrera-R; Wilson Castrillon; Manuel Pastrana; Andres F. Yepes; Wilson Cardona-G

32. Investigation and Comparison of the Effect of TGF-β3, kartogenin and Avocado/Soybean Unsaponifiables on the In-vitroand In-vivo Chondrogenesis of Human Adipose-Derived Stem Cells on Fibrin Scaffold

Pages 368-380

Batool Hashemibeni; Mohammad Ali Izadi; Ali Valiani; Ibrahim Esfandiari; Hamid Bahramian; Hengameh Dortaj; Majid Pourentezari

33. Self-emulsifying Drug Delivery System for Improved Dissolution and Oral Absorption of Quetiapine Fumarate: Investigation of Drug Release Mechanism and In-vitro Intestinal Permeability

Pages 381-398

Olfa Ben Hadj Ayed; Mohamed Ali Lassoued; Badr Bahloul; Souad Sfar

34. The SARS-Cov-2 Proliferation Blocked by a Novel and Potent Main Protease Inhibitor via Computer-aided Drug Design

Pages 399-418

Sepideh Shayan; Shahab Jamaran; Rafee Habib Askandar; Arian Rahimi; Azam Elahi; Chiako Farshadfar; Noeman Ardalan

35. Lapachol-Induced Upregulation of Sirt1/Sirt3 is linked with Improved Skin Wound Healing in Alloxan-induced Diabetic Mice

Pages 419-430

Shaheen Bibi; Fayyaz Ahmad; Muhammad Rizwan Alam; Muhammad Ansar; Sun Yeou Kim; Hussain Mustatab Wahedi

36. The Effect of acetyl-L-carnitine, Alpha-lipoic Acid, and Coenzyme Q10 Combination in Preventing Anti-tuberculosis Drug-induced Hepatotoxicity: A Randomized, Double-blind, Placebo-controlled Clinical Trial

Pages 431-440

Reza Hakimizad; Rasool Soltani; Farzin Khorvash; Majid Marjani; Farzaneh Dastan

37. Standardization of Juniperus macrocarpa Sibt. & Sm. and Juniperus excelsa M. Bieb. Extracts with Carbohydrate Digestive Enzyme Inhibitory and Antioxidant Activities

Pages 441-455

Hasya Nazlı Gök; Nilüfer Orhan; Burçin Özüpek; Sultan Pekacar; Şeyma Nur Selvi; Didem Deliorman Orhan

38. Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking

Pages 456-475

Elmira Meghrazi Ahadi; Homa Azizian; Vaezeh Fathi Vavsari; Atousa Aliahmadi; Zeinab Shahsavari; Hamid R. Bijanzade; Saeed Balalaie

39. Anti-Helicobacter pylori Compounds from Oliveria decumbens Vent. through Urease Inhibitory In-vitro and In-silico Studies

Pages 476-489

Mahdieh Eftekhari; Mohammad Reza Shams Ardekani; Mohsen Amin; Mahboubeh Mansourian; Mina Saeedi; Tahmineh Akbarzadeh; Mahnaz Khanavi

40. Electrochemical Measurement of Noscapine and Lorazepam Using a Carbon Paste Electrode Modified with Multi-walled Carbon Nanotubes and Natural Deep Eutectic Solvent

Pages 490-505

Maryam Vafadar; Ebrahim Zarei; Alireza Asghari

41. Cytotoxicity and Immunogenicity Evaluation of Synthetic Cell-penetrating Peptides for Methotrexate Delivery

Pages 506-515

Parvin Zakeri-Milani; Saeedeh Najafi-Hajivar; Muhammad Sarfraz; Ali Nokhodchi; Hamed Mohammadi; Soheila Montazersaheb; Mehri Niazi; Maryam Hemmatzadeh; Mehdi Soleymani-Goloujeh; Behzad Baradaran; Javid Shahbazi Mojarrad; Masoud Farshbaf; Tooba Gholikhani; Hadi Valizadeh

42. Phenanthrotriazine Derivatives Containing Arylidine Hydrazone Moieties as Novel Potential c-Met Inhibitors with Anticancer Effect

Pages 516-531

Najmeh Edraki; Mohammad Hasan Jamei; Zahra Haghighijoo; Zahra Kayani; Elaheh Raufi; Masoomeh Eskandari; Maryam Firouzi; Hossein Sadeghpur; Ramin Miri; Mehdi Khoshneviszadeh; Omidreza Firuzi

43. Anti-inflammatory Effect of Metronidazole in Hospitalized Patients with Pneumonia due to COVID-19

Pages 532-540

Muhanna Kazempour; Hossein Izadi; Arezoo Chouhdari; Morteza Rezaeifard

44. Development and Validation of four Nitrosamine Impurities Determination Method in Medicines of Valsartan, Losartan, and Irbesartan with HPLC-MS/MS (APCI)

Pages 541-552

Mikhail Khorolskiy; Galina Ramenskaya; Alexander Vlasov; Oleg Perederyaev; Nataliya Maslennikova

45. The Effect of Exogenous Surfactant on Moderate and Severe Stages of COVID-19 Induced ARDS: the Pilot Study of a Clinical Trial

Pages 553-559

Kamal Fani; Mehdi Ghahremani; Mohammad Fathi; Nilofar Massoudi; Sasan Tavana; Navid Nooraee; Nasser Malekpour Alamdari; Sara Besharat; Arash Najafi Abrandabadi; Ali Pirsalehi; Mohammad Ali Khabiri Khatiri; Maryam Amini Pouya; Samira Rajaei; Ali Dabbagh

46. Response Surface Study on Molecular Docking Simulations of Citalopram and Donepezil as Potent CNS Drugs

Pages 560-576

Radin Alikhani; Ahmad Ebadi; Pari Karami; Sara Shahanipour; Nima Razzaghi-Asl

47. CYP2E1 inhibition and NF_κB Signaling Pathway are Involved in the Protective Molecular Effect of Origanum floribundum against Acetaminophen-induced acute Hepatotoxicity in Rats

Pages 577-591

Amina Khelfallah; Bakhta Aouay; Mohamed Kebieche; Fetoui Hamadi

48. Improved Ocular Bioavailability of Moxifloxacin HCl using PLGA Nanoparticles: Fabrication, Characterization, In-vitro and In-vivo Evaluation

Pages 592-608

Fahim Ullah Khan; Fazli Nasir; Zafar Iqbal; Steven Neau; Ismail Khan; Mohammad Hassan; Muhammad Iqbal; Aman Ullah; Sumaira Irum Khan; Mirina Sakhi

49. Evaluation of Inflammasome Activation in Peripheral Blood Mononuclear Cells of Hemodialysis Treated Patients with Glomerulonephritis

Pages 609-617

Atieh Hashemi; Razieh Bigdeli; Masoumeh Shahnazari; Farshid Oruji; Somayeh Fattahi; Erfan Panahnejad; Ayda Ghadri; Elmira Movahedi-Asl; Masoumeh Mahdavi-Ourtakand; Vahid Asgary; Fahimeh Baghbani-Arani