Flavones and Flavone Glycosides from Salvia macrosiphon Boiss

Document Type : Research article


1 Medicinal Plants Research Center, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Tehran, Iran.

2 Department of Chemistry, Faculty of Sciences, Payame Noor University, Sari, Iran

3 Gonbad Institute of Higher Education, Gonbad, Iran

4 Institute of Medicinal Plants, ACECR, Tehran, Iran.


Salvia genus, which is generally called Maryam-Goli in the Persian language, belongs to Lamiaceae family and comprises 58 species in Iran. Four flavonoids plus a steroid compound were isolated from the ethyl acetate and methanol extracts of the aerial parts of Salvia macrosiphon Boiss, using different chromatographic methods on the silica gel and sephadex LH20. The structures of the isolated compounds were determined to be apigenin-7, 4\"-dimethyl ether (1), ?-sitosterol (2), salvigenin (3) apigenin-7-O-glucoside (4) and luteolin-7-O-golucoside (5) using the 1H, 13C-NMR and MS spectra in comparison with those reported in the literature.