Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
2nd International Congress on Traditional Medicine and Materia Medica
Antibacterial activity of Pentanema divaricata ethanol extract and its fractions
Kamalinia G.1, Moosivand A.1, Shahverdi S.2, Monsef H.R.2, Attar F.3, Zarrini Gh.1, Shahverdi A.R.1
1Department of Pharmaceutical Biotechnology and 2Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran 3Central Herbarium, Faculty of Sciences, University of Tehran, Iran
In the past few years, the world has taken a new view to herbal remedies and their applications and many researchers in various fields of medicine are studying this subject. In our program searching for antibacterial agents we have selected an extract prepared from the Pentanema divaricata. No report on the antibacterial activity of this species has been published in literature.
Pentanema divaricata was collected from the around of Shiraz, Iran and identified. This plant was tested for its antibacterial activity on different bacterial species. The whole plant was used in this experiment and extracted with methanol (yield 13%). The methanol extract was partitioned in succession with different solvents. A notable effect was observed on gram-positive bacterial species
Our results suggest that the methanol extract of Pentanema divaricata has an antibacterial activity, which is distributed in the non-polar fractions.