Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
2nd International Congress on Traditional Medicine and Materia Medica
Evaluation of antibacterial activity of extract of Curcuma amada against Staphylococcus aureus
Attarpour Yazdi M.M., Mansouri S., M.Kamalinejad M.
Dep. of Microbiology, Faculty of Medicine, Shahed University, Tehran, Iran
Staphylococcus aureus is an important pathogen and produces a widespread infection. Increasing usage of antibiotic for staphylococcus aureus infections has created antibiotic resistance and subsequently new antibiotics should be produceed. Medicinal herbs with antimicrobial activity have had important roles in traditional medicine. The purpose of this study was to determine the antibacterial activity of hydroalcholic extract root of Curcuma amada against staphylococcus sureus (25923 ATTC).
The roots of C. amada were collected from India and its hyroalcololic extract was obtained and then antibacterial activity against S.aureus was evaluated by disk diffusion and broth serial dilution methods for determining of MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration).
The results from the antibacterial tests demonstrated that the C. amada hydroalcoholic extract is effective against staphylococcus aureus. The MIC and MBC of the extract against staphylococcus aureus were 2.5 and 5 mg/ml, respectively.
This study demonstrated that hydroalcoholic extract of C.amada have excellent antibacterial activities against staphylococcus aureus and are beneficial to human health. They have the potential to be used for medical purposes and to be utilized as antibacterial additives in making paper products. However, we need more investigation in vitro and in vivo.