Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
2nd International Congress on Traditional Medicine and Materia Medica
Evaluation of some Iranian plants for in vitro antiplasmodial activitie
Naghibi F.1, Mosaddegh M.1, Feizhaddad M.H.2, Wright C.W.2, Phillips R.3, Sharifabadi A.D.1
1Traditional Medicine & Materia Medica Research Center, School of Pharmacy, Shaheed Beheshti University of Medical Sciences, Tehran, Iran 2The School of Pharmacy and 3The Tom Connors Cancer Research Center, University of Bradford, West Yorkshire, UK
Fourteen plant species collected in Iran and selected mainly on the basis of their antimicrobial and/or antifungal activities were evaluated for in vitro antiplasmodial and cytotoxic effects in a study designed to screen plant extracts with selective activity against Plasmodium falciparum. The methanol extracts of nine of the species tested exhibit activity against Plasmodium falciparum (MIC values <50 ug/ml).