Taherian, A., Vafaei, A., Rashidy-Pour, A., Sadeghi, H. (2010). Assessment of hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate and tail flick in mice. Iranian Journal of Pharmaceutical Research, Volume 3(Supplement 2), 61-61.
AA Taherian; AA Vafaei; A Rashidy-Pour; H Sadeghi. "Assessment of hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate and tail flick in mice". Iranian Journal of Pharmaceutical Research, Volume 3, Supplement 2, 2010, 61-61.
Taherian, A., Vafaei, A., Rashidy-Pour, A., Sadeghi, H. (2010). 'Assessment of hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate and tail flick in mice', Iranian Journal of Pharmaceutical Research, Volume 3(Supplement 2), pp. 61-61.
Taherian, A., Vafaei, A., Rashidy-Pour, A., Sadeghi, H. Assessment of hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate and tail flick in mice. Iranian Journal of Pharmaceutical Research, 2010; Volume 3(Supplement 2): 61-61.
Assessment of hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate and tail flick in mice
Since use of antinociceptive chemical drugs for relief of pain have many side effects, medical plants seem very noticeable today. Previous findings indicate that Foeniculum vulgare (FV) modulates pain in both animal and human. The present work investigated the effects of Hydoalcoholic extract of FV on acute pain in Hot plate and Tail flick models.
Albino mice (20-30 gr) were used for this study. Hydroalcoholic extract of FV seed was injected in doses of 200 and 500 mg/kg 30 min before test. Then the analgesic effect of the drug on acute pain was evaluated using Hot plate and Tail flick models
Results indicated that FV has analgesic effect in both doses in both models (P<0.01).
Finding above showed that FV can modulate acute pain. Further research is required to determine the mechanisms by which FV has an inhibitory effect on pain sensation.
Full Text
Iranian Journal of Pharmaceutical Research (2004): Supplement 2
Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
61-61
Poster Presentations/Ethnopharmacology
2nd International Congress on Traditional Medicine and Materia Medica October 4-7, 2004, Tehran, Iran
182
Assessment of
hydroalcoholic extract of Foeniculum vulgare on acute pain in hot plate
and tail flick in mice
Taherian A.A., Vafaei A.A.,
Rashidy-Pour A., Sadeghi H.
Department of
Physiology and Pharmacology, Faculty of Medicine, University of Medical
Sciences, Semnan, Iran
Since use of antinociceptive chemical drugs for relief of pain have many side
effects, medical plants seem very noticeable today. Previous findings indicate
that Foeniculum vulgare (FV) modulates pain in both animal and human. The
present work investigated the effects of Hydoalcoholic extract of FV on acute
pain in Hot plate and Tail flick models.
Albino mice (20-30 gr) were used for this study. Hydroalcoholic extract of FV
seed was injected in doses of 200 and 500 mg/kg 30 min before test. Then the
analgesic effect of the drug on acute pain was evaluated using Hot plate and
Tail flick models
Results indicated that FV has analgesic effect in both doses in both models
(P<0.01).
Finding above showed that FV can modulate acute pain. Further research is
required to determine the mechanisms by which FV has an inhibitory effect on
pain sensation.
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