Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
2nd International Congress on Traditional Medicine and Materia Medica
Effect of Beta vulgaris extract on triglyceride and cholesterol in diabetic male rats
Khalili M., Vaez Mahdavi M.R.
Department of Physiology, School of Medicine, Shahed University
Beta vulgaris (Bv) was introduced as an antidiabetic herb in Iranan medicinal plant. Regarding to the effect of Bv on diabetes rats, we investigated that whether this plant could decrease the augmented triglyceride and cholesterol, which produce by diabetes. However, if this plant would be able to decrease the triglyceride and cholesterol, it can be introduced as a useful component for these patients.
In the present study four groups 1-Control 2-Diabetes 3-Control+Extract 4-Diabetes+Extract were chosen. The animals were made diabetic by injection of Stereptozotocin (STZ) 60 mg/kg, i.p. The rats 30 days following STZ application became diabetic. For checking of diabetes, the animal’s blood glucose was measured by special kit. In treatment group, the extract was applied to the animals in i.p one other day for 30 days. In the end of 30 days triglyceride and cholesterol from each group was measured by their special kits and compared with others.
In our experiment the augmented triglyceride and cholesterol due to diabetes were significantly decreased by application of Bv extract.
Beta vulgaris extract as an anti-diabetic component could decrease triglycerid and cholesterol in both control and diabetes groups markedly.