Bayat, M., Khoshvaghti, A. (2010). Quantitative changes of mast cells following topical application of honey on third degree burns in rats. Iranian Journal of Pharmaceutical Research, Volume 3(Supplement 2), 45-45.
M Bayat; A Khoshvaghti. "Quantitative changes of mast cells following topical application of honey on third degree burns in rats". Iranian Journal of Pharmaceutical Research, Volume 3, Supplement 2, 2010, 45-45.
Bayat, M., Khoshvaghti, A. (2010). 'Quantitative changes of mast cells following topical application of honey on third degree burns in rats', Iranian Journal of Pharmaceutical Research, Volume 3(Supplement 2), pp. 45-45.
Bayat, M., Khoshvaghti, A. Quantitative changes of mast cells following topical application of honey on third degree burns in rats. Iranian Journal of Pharmaceutical Research, 2010; Volume 3(Supplement 2): 45-45.
Quantitative changes of mast cells following topical application of honey on third degree burns in rats
The purpose of present study was determination of number changes of mast cells in a honey treated experimental model of third degree burn.
A third degree burn was made in 24 adult female rats by direct contact of skin with boiling water for 8 seconds. Rats were divided randomly into four groups. Group 1: Burns of this group remained untreated (control group). Groups 2 and 3: Burns of these groups were received topical application of unboiled commercial honey one-time per day and twice daily. Group 4: Burns of this group were received topical application of nitrofurazone cream daily (routine treatment). Samples were extracted from 3 rats at day 15 and of another 3 rats at day 30. Samples were processed for light microscopy study and stained with toluidine blue. Mast cells were counted by a calibrated light microscope. Data were analyzed by Mann-Whitney U test.
Group 4 had highest number of mast cells at day 15 (30.43±41.1) and at day 30 (31.52±41.1). Control group had lowest number of mast cells at day 15 (11.9±15.43). Group 2 had lowest number of mast cells at day 30 (17.19±22.85).
It is concluded that topical application of honey on third degree burns didn’t have significant effect on the number of mast cells in comparison with control and routine treatment groups.
Full Text
Iranian Journal of Pharmaceutical Research (2004): Supplement 2
Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
45-45
Poster Presentations/Ethnopharmacology
2nd International Congress on Traditional Medicine and Materia Medica October 4-7, 2004, Tehran, Iran
128
Quantitative changes
of mast cells following topical application of honey on third degree burns in
rats
Bayat M., Khoshvaghti A.
Cellular and
Molecular Biology Research Center, Medical Faculty, Shaheed Beheshti University
of Medical Sciences, Tehran, Iran
The purpose of present study was determination of number changes of mast cells
in a honey treated experimental model of third degree burn.
A
third degree burn was made in 24 adult female rats by direct contact of skin
with boiling water for 8 seconds. Rats were divided randomly into four groups.
Group 1: Burns of this group remained untreated (control group). Groups 2 and 3:
Burns of these groups were received topical application of unboiled commercial
honey one-time per day and twice daily. Group 4: Burns of this group were
received topical application of nitrofurazone cream daily (routine treatment).
Samples were extracted from 3 rats at day 15 and of another 3 rats at day 30.
Samples were processed for light microscopy study and stained with toluidine
blue. Mast cells were counted by a calibrated light microscope. Data were
analyzed by Mann-Whitney U test.
Group 4 had highest number of mast cells at day 15 (30.43±41.1) and at day 30
(31.52±41.1). Control group had lowest number of mast cells at day 15
(11.9±15.43). Group 2 had lowest number of mast cells at day 30 (17.19±22.85).
It
is concluded that topical application of honey on third degree burns didn’t have
significant effect on the number of mast cells in comparison with control and
routine treatment groups.
Top