Iranian Journal of Pharmaceutical Research (2004): Supplement 2:
2nd International Congress on Traditional Medicine and Materia Medica
Comparison of the effect of Hirudo medicinals and Pyroxicam capsule on reduction of inflamation and pain in the primary stages of rheumatoid arthritis of knee
Zarrin Ghalam Moghaddam J.1, Naghade M.2
1Shahid Beheshti University of Medical Sciences 2Departmant of Phisyology, Faculty of Medicine, Tabriz University of Medical Sciences
The rheumatoid arthritis is one of the most prevalent feeling incomidity and sever pain in the joint of the knee among individuals whom it is considered as the weakner illness, because of decisive being undistiguished its cause of beginning illness, severe pain, long trip, and its destructive role. The different treatments are considered to cease or retard this illness process but what it appears to be abvious is that all treatments primarely lead to slow down pain and inflammation of joints and tissues involved in this group of patients. To do this we also decided to compare the effect of hirudo medicinalis (H.M) and piroxicom capsule (between the NSAIDS drugs group) on minimum of pain and inflammation in the primary illness stages in the patients with the rheumatoid arthritis of the knee.
In this study, we selected 100 cases of patients with the rheumatoid artheritis of knee that they had the clinical and para clinical evidance indicating the knee sizure (one or both of them) to the rheumatoid arthritis. 44 male and 56 female are selected who had the average age 47, that the minimum and maximum of ages were 38 and 56. The average of weight was 60 kg. Non of them didnot have the apparent symptoms indicating the joint deformation and solidity and they were being traversing the primery illness stages and didnot have precedent of consuming drug in order to treat the mentioned illness since two mounth ago.50 person selected randomly for piroxicom treatment and second 50 body for H.M.
Four of cases among the group under piroxicom treatment had a complete reduction of pain and inflammation in the joint while 21 of them had a relative reduction and 25 of them stayed without effect but in the second group, 36 person of cases had complete reduction of pain and 10 of cases had relative reduction of pain and 4 of them steyed without effect due to H.M treatment.
The available materials in hirodu medisinalis saliva (leeches) will be mre effective and permanent in reduction of inflammatory pains due to reumatoid arthritis of knee (first stages) than treatment by the use of piroxicom capsule in certain perid in attention of the performed investigation.