Meechai, I., phupong, W., Chunglok, W., Meepowpan, P. (2018). Dihydroosajaxanthone: A New Natural Xanthone from the Branches of Garcinia Schomburgkiana Pierre. Iranian Journal of Pharmaceutical Research, 17(4), 1347-1352. doi: 10.22037/ijpr.2018.2292
Imron Meechai; worrapong phupong; Warangkana Chunglok; Puttinan Meepowpan. "Dihydroosajaxanthone: A New Natural Xanthone from the Branches of Garcinia Schomburgkiana Pierre". Iranian Journal of Pharmaceutical Research, 17, 4, 2018, 1347-1352. doi: 10.22037/ijpr.2018.2292
Meechai, I., phupong, W., Chunglok, W., Meepowpan, P. (2018). 'Dihydroosajaxanthone: A New Natural Xanthone from the Branches of Garcinia Schomburgkiana Pierre', Iranian Journal of Pharmaceutical Research, 17(4), pp. 1347-1352. doi: 10.22037/ijpr.2018.2292
Meechai, I., phupong, W., Chunglok, W., Meepowpan, P. Dihydroosajaxanthone: A New Natural Xanthone from the Branches of Garcinia Schomburgkiana Pierre. Iranian Journal of Pharmaceutical Research, 2018; 17(4): 1347-1352. doi: 10.22037/ijpr.2018.2292
Dihydroosajaxanthone: A New Natural Xanthone from the Branches of Garcinia Schomburgkiana Pierre
1Department of Chemistry, School of Science, Walailak University, Nakhon Si Thammarat, 80161, Thailand.
2Department of Medical Technology, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, 80161 Thailand.
3Department of Chemistry, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand.
Abstract
Garcinia schomburgkiana, locally known in Thailand as an edible fruit “Ma-dan”, is a plant species of the Clusiaceae family which has been reported as sources of a variety of compounds with biological activities. In the phytochemical studies of Ma-dan, four xanthones were, for the very first time, isolated from the branch acetone extract of G. schomburgkiana. Their structures were determined through the analysis of spectroscopic data (1H, 13C-NMR, IR and MS) and the comparison with those previously reported. Dihydroosajaxanthone (1), an original synthetic xanthone, is reported herein for the first time as a naturally occurring xanthone, together with three known xanthones: xanthochymone A (2), 1,3,7-trihydroxy-2-(3-hydroxy-3-methylbutyl) xanthone (3) and 1,3,5,6-tetrahydroxyxanthone (4). These compounds, especially dihydroosajaxanthone (1), might be considered as chemotaxonomic markers of the Garcinia genus.
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