Exposure Assessment for Some Pesticides through Rice Consumption in Iran Using a Multiresidue Analysis by GC-MS

Document Type: Research article

Authors

1 Food and Drug Laboratories Research Center, Ministry of Health and Medical Education, Tehran, Iran.

2 Food and Drug Control Laboratories, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran.

3 Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Department of Toxicology and Pharmacology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Department of Medicinal Chemistry, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

6 Phytochemistry Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

7 Department of Medicinal Chemistry, School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

8 Food and Drug Control Laboratories, Food and Drug Administration, Ministry of Health and Medical Education, Tehran, Iran

Abstract

In communities which consume rice as main food, importance of risk assessment for
contaminants is always taken into consideration by health authorities. The present study is
an attempt for monitoring of 56 pesticides from different chemical groups in rice samples
collected from local markets in Tehran and estimation of daily intake of interested pesticides
through this monitoring. A valid method based on spiked calibration curves and QuEChERS
sample preparation was developed for determination of pesticides residue in rice by GC/MS.
The analytical results of the proposed method were in good agreement with the proficiency test
(FAPAS 0969). One-hundred-thirty-five rice samples were analyzed and 11 pesticide residues
were found in 10.4% of the samples. Of which 5.2% were contaminated with unregulated
pesticides. None of the samples, which were contaminated with regulated pesticides, had
contamination higher than maximum residue limit. The mean estimated dose (ED) was
calculated with respect of mean of contamination and mean daily consumption of rice. ED of
the found pesticides is much lower than the related ADIs.

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