Study of the Effect of an Oral Formulation of Fig and Olive on Rheumatoid Arthritis (RA) Remission Indicators: A Randomized Clinical Trial

Document Type: Research article

Authors

1 Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran.

2 Food Safety Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Department of Pharmacognosy, School of pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

5 Department of Physiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

6 Department of Rheumatology, Loghman-e Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Abstract

This study was designed to explore the complementary effects of a combination formulation of olive oil, olive and fig fruits on RA remission indicators. A randomized controlled clinical trial was designed. Adult RA patients were randomly divided into two groups receiving routine Disease-modifying antirheumatic drugs (DMARDs) regimen (control group) and routine DMARDs regimen plus the herbal supplementary formulation of olive oil, fig and olive fruits (intervention group). Patients were followed every 4 weeks for total study period of 16 weeks. In addition to demographic and medical history of the patients, the Disease Activity Score with 28-joint counts based on Erythrocyte Sedimentation Rate (DAS28_ESR) were recorded. SPSS (version 22.0) software was used to analyze data, assuming p

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