The Effects of Selected Hot and Cold Temperament Herbs Based on Iranian Traditional Medicine on Some Metabolic Parameters in Normal Rats

Document Type: Research article

Authors

1 Department of Traditional Pharmacy, School of Traditional Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Endocrine Physiology Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Deptartment of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Abstract

This study was aimed to evaluate the effects of diets containing some hot and cold
temperament herb seeds according to Iranian traditional medicine (ITM) on some metabolic
parameters in acute (24 h) and sub-acute (7 day) experiments that were performed on rats. For
each experiment, effects of diets containing 10% herb seeds in category of hot (anise, fennel,
ajowan) and cold (cucumber, watermelon, pumpkin) temperaments were analyzed on body
weight gain, food intake, water consumption, urine output, serum glucose (SG) and insulin
levels of rats. In the acute experiment, anise or fennel fed groups showed a significant decrease
in food intake and there were not any changes in other parameters. The hot temperament groups
in comparison with the cold temperament ones showed a significant decrease in food intake
and a significant increase in SG level. In the sub-acute experiment, anise and fennel fed groups
had a significant decrease in body weight gain on the 4thday. On the 7th day, the anise fed group
experienced a significant decrease in body weight gain and a significant increase in SG levels.
The groups that were fed hot temperament diets compared to the ones that consumed cold
temperament diets showed a significant decrease in body weight gain and food intake rates and
a considerable increase in SG levels. Considering the findings of this study, one can conclude
that it is possible that hot temperament herbs such as anise and fennel be useful for humans for
certain conditions such as weight control.

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