Characterization and antibacterial activity of phthalides from the roots of the medicinal herb Levisticum officinale W.D.J. Koch.

Document Type: Research article

Authors

• Mansour Miran ¹
• Hamid Reza Monsef Esfahani ²
• Jee H. Jung ³
• Atousa Aliahmadi ⁴
• Danielle Skropeta ⁵
• Mahdi Abbas-Mohammadi ⁶
• Samad Nejad Ebrahimi ⁷
• Mahdi Moridi Farimani ⁸

¹ Department of Pharmacognosy and Biotechnology, School of Pharmacy, Ardabil University of Medical Sciences, Ardabil, Iran.

² Department of Pharmacognosy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

³ College of Pharmacy, Pusan National University, Busan, South Korea.

⁴ Department of Biology, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University

⁵ Molecular Horizons and School of Chemistry & Molecular Bioscience, University of Wollongong, Wollongong, NSW 2500, Australia.

⁶ Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, G.C., Evin, Tehran, Iran.

⁷ Medicinal Plants and Drugs Res. Inst. Shahid Beheshti University, Velenjak, Tehran

⁸ Department of Phytochemistry, Medicinal Plants and Drugs Research Institute, Shahid Beheshti University, Tehran, Iran.

Abstract

Graphical Abstract

Keywords

• Levisticum officinale
• phthalide
• antibacterial activity
• 2D NMR
• structure elucidation