Isolation and Identification of Flavonol Glycosides from Lathyrus Armenus (Boiss. & Huet)

Document Type: Research article

Authors

1 Ankara University, Faculty of Pharmacy, Department of Pharmacognosy, Ankara, Turkey.

2 Trakya University, Faculty of Pharmacy, Department of Pharmaceutical Botany, Edirne, Turkey.

Abstract

In the last five decades study on plant secondary metabolites have been increasing. Higher plants with a wide range of secondary metabolites have been very important in the search of new therapeutic agents. Flavonoids are most widely distributed secondary natural metabolites that found in plants which occuring in free forms or as glycosides with polyphenolic structure. In this study secondary metabolites of Lathyrus armenus (Boiss. & Huet) which endemic for Turkey was studied. Flavonol glycosides (Rhamnocitrin-3-O-rhamninoside, Rhamnetin-3-O-rhamninoside, Rhamnazin- 3-O-rhamninoside, kaempferol3-O-rhamninoside and, kaempferol-3-O-glucosyl (1→2) rhamnoside) was isolated by different chromatographic methods and identified by 1H, 13C NMR, as well as 2D NMR and Mass spectroscopy techniques from ethyl acetate and aqueous fractions of L. armenus’s methanolic extract. This is the first study about secondary metabolites of Turkish Lathyrus species.

Graphical Abstract

Isolation and Identification of Flavonol Glycosides from Lathyrus Armenus (Boiss. & Huet)

Keywords