References
World Cancer Report, 2015; (Accessed March 15,
2016). Available from: URL: http://www.iarc.fr/en/
publications /books/wcr/wcr-order.php.
Vignesh G, Senthilkumar R, Paul P, Periasamy VS,
Akbarsha MA and Arunachalam S. Protein binding
and biological evaluation of a polymer-anchored
cobalt (III) complex containing a 2,20-bipyridine
ligand. RSC Adv. (2014) 4: 57483-92.
Samie N, Haerian BS, Muniandy S, Marlina A,
Kanthimathi MS, Abdullah NB, Ahmadian G and
Aziddin RER. Mechanism of Action of the Novel
Nickel (II) Complex in Simultaneous Reactivation
of the Apoptotic Signaling Networks Against Human
Colon Cancer Cells. Front. Pharmacol. (2016) 6: 313.
Qi J, Zhang Y, Gou Y, Zhang Z, Zhou Z, Wu X, Yang
F and Liang H. Developing an Anticancer Copper(II)
(1)
(2)
(3)
(4)
Pro-Drug Based on the His242 Residue of the Human
Serum Albumin Carrier IIA Subdomain. Mol. Pharm.
(2016) 13: 1501-7 .
Aydın A, Korkmaz N, Tekin Ş and Karadağ A.
Anticancer activities and mechanism of action of
2 novel metal complexes, C16H34N8
O5
Ag2
Cd and
C11H16N7
O2
Ag3
Ni. Turk J. Biol. (2014) 38: 948-55.
Korkmaz N, Karadağ A, Aydın A, Yanar Y, Karaman
İ and Tekin Ş. Synthesis and characterization of two
novel dicyanidoargentate(I) complexes containing
N-(2-hydroxyethyl)ethylenediamine exhibiting
significant biological activity. New J. Chem. (2014)
38: 4760-73.
Tekin S, Aydın A, Dede S and Karadağ A. Antiproliferative activity of a new coordination compound
containing AuI
(CN)2
in some cancer cell lines. J.
Biotechnol. (2014) 185: 28-9.
Aydın A, Karadağ A, Tekin Ş, Korkmaz N and Özdemir
A. Two new coordination polymers containing
dicyanidoargentate(I) and dicyanidoaurate(I):
synthesis and characterization, and a detailed in-vitro
investigation of their anticancer activities on some
cancer cell lines. Turk. J. Chem. (2015) 39: 532-49
Karadağ A, Aydın A, Özdemir A and Tekin Ş.
Antiproliferative and cytotoxic activities of a new
cyanido coordination compound on several cancer cell
lines. J. Biotechnol. (2014) 185: 105.
Gielen M and Tiekink ERT. Metallotherapeutic Drugs
and Metal-Based Diagnostic Agents: The Use of
Metals in Medicine. John Wiley & Sons press, 644 p,
West Sussex (2005) 1-560.
Avendano C and Menéndez JC. Medicinal Chemistry
Of Anticancer Drugs. Elsevier science press, 1st
edition, 400 p, Amsterdam (2008) 1-429.
Dabrowiak JC. Metals in Medicine. John Wiley &
Sons, 1st Edition, 321 p, West Sussex (2009) 1-310.
Karadağ A, Aydın A, Dede S, Tekin Ş, Yanar Y,
Çadırcı BH, Soylu MS and Andaç Ö. Five Novel
Dicyanidoaurate(I)-Based Complexes Exhibiting
Significant Biological activities: Synthesis,
Characterization and Three Crystal Structures. New J.
Chem. (2015) 39: 8136-52.
Karadağ A, Aslan Korkmaz Ş, Andaç Ö, Yerli Y
and Topcu Y. Cyano-complexes and salts with
tetracyanonickellateII and N,N-bis(2-hydroxyethyl)-
ethylenediamine: synthesis, IR spectra, magnetic
properties, thermal analyses, and crystal structures. J.
Coord. Chem. (2012) 65: 1685-99.
Aslan Korkmaz Ş, Karadağ A, Korkmaz N, Andaç Ö,
Gürbüz N, Özdemir İ and Topkaya R. Five complexes
containing N,N-bis(2-hydroxyethyl)-ethylenediamine
with tetracyanidopalladate(II): synthesis, crystal
structures, thermal, magnetic, and catalytic properties.
J. Coord. Chem. (2013) 66: 3072-91.
Aslan Korkmaz Ş, Karadağ A, Yerli Y and Soylu
MS. Synthesis and characterization of new
heterometallic cyanido complexes based on
[Co(CN)6
]3- building blocks: crystal structure of
[Cu2
(N-bishydeten)2
Co(CN)6
].3H2
O having a strong
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
(14)
(15)
(16)
Pharmacological capacity of some heterobimetallics
2027
antiferromagnetic exchange. New J. Chem. (2014) 38:
5402-10.
Porstmann T, Ternynck T and Avrameas S. Quantitation
of 5-bromo-2-deoxyuridine incorporation into DNA:
an enzyme immunoassay for the assessment of the
lymphoid cell proliferative response. J. Immunol.
Methods (1985) 82(1): 169-179.
Sgonc R, Boeck G, Dietrich H, Gruber J, Recheis
H and Wick G. Simultaneous determination of cell
surface antigens and apoptosis. Trends Genet. (1994)
10: 41-2.
Gong J, Traganos F and Darzynkiewicz Z. A selective
procedure for DNA extraction from apoptotic cells
applicable for gel electrophoresis and flow cytometry.
Anal. Biochem. (1994) 218: 314-9..
Chen P-S, Shih Y-W, Huang H-C and Cheng H-W.
Diosgenin, a Steroidal Saponin, Inhibits Migration
and Invasion of Human Prostate Cancer PC-3 Cells
by Reducing Matrix Metalloproteinases Expression.
PLoS ONE (2011) 6: e20164.
Park HJ, Lee HJ, Lee E-J, Hwang HJ, Shin S-H,
Suh M-E, Kim C, Kim HJ, Seo E-K and Lee SK.
Cytotoxicity and DNA Topoisomerase Inhibitory
Activity of Benz[f]indole-4,9-dione Analogs. Biosci.
Biotechnol. Biochem. (2003) 67: 1944-9.
Catanzaro JM, Sheshadri N, Pan J-A, Sun Y, Shi C, Li
J, Powers RS, Crawford HC and Zong W-X. Oncogenic
Ras induces inflammatory cytokine production by
up-regulating the squamous cell carcinoma antigens
SerpinB3/B4. Nat. Commun. (2014) 5: 3729.
Wolfe A, Shimer GH and Meehan T. Polycyclic
aromatic hydrocarbons physically intercalate into
duplex regions of denatured DNA. Biochemistry
(1987) 26: 6392-6.
Lakowicz JR and Weber G. Quenching of fluorescence
by oxygen. A probe for structural fluctuations in
macromolecules. Biochemistry (1973) 12: 4161-70.
Sirajuddin M, Ali S and Badshah A. Drug–DNA
interactions and their study by UV–Visible,
fluorescence spectroscopies and cyclic voltammetry.
J. Photochem. Photobiol. B (2013) 124: 1-19.
Kapdi AR and Fairlamb IJS. Anti-cancer palladium
complexes: a focus on PdX2
L2
, palladacycles and
related complexes. Chem. Soc. Rev. (2014) 43: 4751.
Munteanu CR and Suntharalingam K. Advances in
cobalt complexes as anticancer agents. Dalton Trans.
(2015) 44: 13796. 10.
Gao E, Lin L, Liu L, Zhu M, Wang B and Gao
X. Two new palladium(II) complexes: synthesis,
(17)
(18)
(19)
(20)
(21)
(22)
(23)
(24)
(25)
(26)
(27)
(28)
characterization and their interaction with HeLa cells.
Dalton Trans. (2012) 41: 11187-94
Tanaka M, Kataoka H, Yano S, Ohi H, Kawamoto K,
Shibahara T, Mizoshita T, Mori Y, Tanida S, Kamiya
T and Joh T. Anti-cancer effects of newly developed
chemotherapeutic agent, glycoconjugated palladium
(II) complex, against cisplatin-resistant gastric cancer
cells. BMC Cancer (2013) 13: 237.
Tsekova D, Gorolomova P, Gochev G, Skumryevb
V, Momekov G, Momekova D and Gencheva G.
Synthesis, structure and in-vitro cytotoxic studies of
novel paramagnetic palladium(III) complexes with
hematoporphyrin IX. J. Inorg. Biochem. (2013) 124:
54-62.
Keter FK, Kanyanda S, Lyantagaye SSL, Darkwa
J, Rees DJG and Meyer M. In-vitro evaluation of
dichloro-bis(pyrazole)palladium(II) and dichlorobis(pyrazole)platinum(II) complexes as anticancer
agents. Cancer Chemother. Pharmacol. (2008) 63:
127–38.
Narla RK, Chen C-L, Dong Y and Uckun FM.
In-vivo Antitumor Activity of Bis(4,7-dimethyl-1,10-
phenanthroline) Sulfatooxovanadium(IV) {METVAN
[VO(SO4
)(Me2
-Phen)2
]}. Clin. Cancer Res. (2001) 7:
2124-33.
Beshir AB, Guchhait SK, Gascón JA and Fenteany G.
Synthesis and structure-activity relationships of metalligand complexes that potently inhibit cell migration.
Bioorg. Med. Chem. Lett. (2008) 18: 498-504.
Nazarov AA, Baquié M, Nowak-Sliwinska P, Zava O,
van Beijnum JR, Groessl M, Chisholm DM, Ahmadi
Z, McIndoe JS, Griffioen AW, van den Bergh H and
Dyson PJ. Synthesis and characterization of a new
class of anti-angiogenic agents based on ruthenium
clusters. Sci. Rep. (2013) 3: 1485.
Ahmad M, Afzal M, Tabassum S, Kalińska B,
Mrozinski J and Bharadwaj PK. Synthesis and structure
elucidation of a cobalt(II) complex as topoisomerase I
inhibitor: In-vitro DNA binding, nuclease and RBC
hemolysis. Eur. J. Med. Chem. (2014) 74: 683-93.
Chew ST, Lo KM, Lee SK, Heng MP, Teoh WY, Sim
KS and Tan KW. Copper complexes with phosphonium
containing hydrazone ligand: Topoisomerase inhibition
and cytotoxicity study. Eur. J. Med. Chem. (2014) 76:
397-407.
Pages BJ, Ang DL, Wright EP and Aldrich-Wright JR.
Metal complex interactions with DNA. Dalton Trans.
(2015) 44: 3505-26.
)