Author = Afshin Zarghi
Number of Articles: 56
1. Design, Synthesis and Biological Evaluation of 1,3-Diphenyl-3- (phenylthio)propan-1-ones as New Cytotoxic Agents

Volume 20, Issue 4, Autumn 2021, Pages 229-237

Maryam Bayanati; Soraya Shahhosseini; Farshad H Shirazi; Golrokh Farnam; Afshin Zarghi


2. Design, Synthesis, Docking Study and Biological Evaluation of 4-Hydroxy-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide Derivatives as Anti-HIV Agents

Volume 20, Issue 3, Summer 2021, Pages 1-12

Ali Imani; Sepehr Soleymani; Rouhollah Vahabpour; Zahra Hajimahdi; Afshin Zarghi


3. Evaluation of Cytotoxic Potentials of Novel Synthesized Chalconeferrocenyl Derivative against Melanoma and Normal Fibroblast and Its Anticancer Effect through Mitochondrial Pathway

Volume 20, Issue 2, Spring 2021, Pages 241-253

Ahmad Salimi; Mozhgan Ghasempour; Zahra Mousavi; Shabnam Farzaneh; Farzad Khodaparast; Parvaneh Naserzadeh; Afshin Zarghi; Jalal Pourahmad


4. HIV-1 Reverse Transcriptase/Integrase Dual Inhibitors: A Review of Recent Advances and Structure-activity Relationship Studies

Volume 20, Issue 2, Spring 2021, Pages 333-369

Mohammad Mahboubi-Rabbani; Zahra Hajimahdi; Maryam Abbasi; Afshin Zarghi


5. 4-(1-Benzyl-1H-benzo[d]imidazol-2-yl)-4-oxo-2-butenoic Acid Derivatives: Design, Synthesis and Anti-HIV-1 Activity

Volume 20, Issue 1, Winter 2021, Pages 408-417

Nafiseh Karimi; Rouhollah Vahabpour Rodsari; Mahsa Azami Movahed; Zahra Hajimahdi; Afshin Zarghi


6. Naringenin Enhances the Anti-Cancer Effect of Cyclophosphamide against MDA-MB-231 Breast Cancer Cells Via Targeting the STAT3 Signaling Pathway

Volume 19, Issue 3, Summer 2020, Pages 122-133

Shokoofe Noori; Mostafa Rezaei Tavirani; Niloofar Deravi; Mohammad Ismaiil Mahboobi Rabbani; Afshin Zarghi


7. STAT3-mediated apoptotic-enhancing function of sclareol against breast cancer cells and cell sensitization to cyclophosphamide

Volume 19, Issue 1, Winter 2020, Pages 398-412

Havva Afshari; Mitra Nourbakhsh; Niloufar Salehi; Mohammad Mahboubi_Rabbani; Afshin Zarghi; Shokoofe Noori


8. Design, Synthesis, Molecular Modeling Studies and Biological Evaluation of N'-Arylidene-6-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbohydrazide Derivatives as Novel Anti-HCV Agents

Volume 18, Issue 4, Autumn 2019, Pages 1790-1802

Seyyed Mohammad Ismaeil MahboobiRabbani; Roholah Vahabpour Rodsari; Zahra Hajimahdi; Afshin Zarghi


9. Design, Synthesis, Molecular Modeling Study and Biological Evaluation of New N'-arylidene-pyrido[2,3-d]pyrimidine-5-carbohydrazide Derivatives as Anti-HIV-1 Agents

Volume 18, Special Issue, Autumn 2019, Pages 237-248

Elnaz Ebrahimzadeh; Sayyed Abbas Tabatabai; Roholah Vahabpour Rodsari; Zahra Hajimahdi; Afshin Zarghi


10. Molecular Docking and QSAR Study of 2-Benzoxazolinone, Quinazoline and Diazocoumarin Derivatives as Anti-HIV-1 Agents

Volume 18, Issue 3, Summer 2019, Pages 1253-1263

Kamyar Faghihi; Mahdieh Safakish; Tannaz Zebardast; Zahra Hajimahdi; Afshin Zarghi


11. Synthesis, Characterization and In-vitro Evaluation of Novel Naphthoquinone Derivatives and Related Imines: Identification of New Anticancer Leads

Volume 18, Issue 1, Winter 2019, Pages 16-29

Sima Golmakaniyoon; Vahid Reza Askari; Khalil Abnous; Afshin Zarghi; Razieh Ghodsi


12. Design, Synthesis, Molecular Modeling, In Silico ADME Studies and Anti-HIV-1 Assay of New Diazocoumarin Derivatives

Volume 17, Special Issue 2, Autumn 2018, Pages 65-77

Zeynab Alimi Livani; Mahdieh Safakish; Zahra Hajimahdi; Sepehr Soleymani; Rezvan Zabihollahi; Mohammad Reza Aghasadeghi; Eskandar Alipour; Afshin Zarghi


13. Pharmacokinetics and Biodistribution of Pegylated Methotrexate after IV Administration to Mice

Volume 17, Special Issue 2, Autumn 2018, Pages 111-123

Gholamhossein Yousefi; Alireza Shafaati; Afshin Zarghi; Seyed Mohsen Foroutan


14. Design, Synthesis and Biological Evaluation of New Imidazo[2,1-b]Thiazole Derivatives as Selective COX-2 Inhibitors

Volume 17, Issue 4, Autumn 2018, Pages 1288-1296

Mahsa Shahrasbi; Mahsa Azami Movahed; Orkideh Ghorban Dadras; Bahram Daraei; Afshin Zarghi


15. Design, Synthesis and Biological Evaluation of Ketoprofen Conjugated To RGD/NGR for Targeted Cancer Therapy

Volume 17, Issue 4, Autumn 2018, Pages 1297-1305

Bahareh Shokri; Afshin Zarghi; Soraya Shahhosseini; Reza Mohammadi; Farzad Kobarfard


16. Novel Colchicine Analogues Target Mitochondrial PT Pores Using Free Tubulins and Induce ROS-Mediated Apoptosis in Cancerous Lymphocytes

Volume 17, Issue 4, Autumn 2018, Pages 1476-1487

Marjan Aghvami; Peyman Eshghi; Mohammad Hadi Zarei; Hadi Arefi; Fatemeh Sattari; Afshin Zarghi; Jalal Pourahmad


18. Design, Synthesis and Biological Evaluation of Novel Peptide-Like Analogues as Selective COX-2 Inhibitors

Volume 17, Issue 1, Winter 2018, Pages 87-92

Mohammad Ali Ahmaditaba; Mohammad Hassan Houshdar Tehrani; Afshin Zarghi; Soraya Shahhosseini; Bahram Daraei


19. Physicochemical, Stress Degradation Evaluation and Pharmacokinetic Study of AZGH101; a New Synthesized COX2 Inhibitor after I.V. and Oral Administration in Male and Female Rats

Volume 17, Issue 1, Winter 2018, Pages 115-123

Hoda Bahmanof; Simin Dadashzadeh; Afshin Zarghi; Alireza Shafaati; Mohsen Foroutan


20. Physicochemical, stress degradation evaluation and pharmacokinetic study of AZGH102, a new synthesized COX2 inhibitors after I.V. and oral administration in male and female rats

Volume 16, Issue 2, Spring 2017, Pages 442-450

Hoda Bahmanof; Simin Dadashzadeh; Afshin Zarghi; Alireza Shafaati; Mohsen Foroutan


21. QSAR Modeling of COX-2 Inhibitory Activity of Some Dihydropyridine and Hydroquinoline Derivatives Using Multiple Linear Regression (MLR) Method

Volume 16, Issue 2, Spring 2017, Pages 525-532

Somaye Akbari; Tannaz Zebardast; Afshin Zarghi; Zahra Hajimahdi


22. A Simple and Specific Stability- Indicating RP-HPLC Method for Routine Assay of Adefovir Dipivoxil in Bulk and Tablet Dosage Form

Volume 16, Issue 1, Winter 2017, Pages 132-139

Bahar Darsazan; Alireza Shafaati; Seyed Alireza Mortazavi; Afshin Zarghi


23. Progress in HIV-1 integrase inhibitors: A review of their chemical structure diversity

Volume 15, Issue 4, Autumn 2016, Pages 595-628

Afshin Zarghi; Zahra Hajimahdi


24. Design and Synthesis of Pyrrolo[2,1-a]Isoquinoline-Based Derivatives as New Cytotoxic Agents

Volume 15, Issue 4, Autumn 2016, Pages 743-751

Afshin Zarghi; Samaneh Kakhki; Sorayya Shahosseini


25. QSAR Analysis for Some 1, 2-Benzisothiazol-3-one Derivatives as Caspase-3 Inhibitors by Stepwise MLR Method

Volume 15, Issue 2, Spring 2016, Pages 439-448

Zahra Hajimahdi; Fatemeh Safizadeh; Afshin Zarghi